BioMend : Features & Benefits
Material Description
The BioMend absorbable collagen membrane is a compressed, non-friable Type I collagen matrix derived from bovine Achilles tendon.
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The product is paper-white in the dry state with a surface texture similar to leather. In cross-section, the composition of condensed, laminated sheets is visible. The BioMend membrane becomes translucent when hydrated but remains non-slippery and adaptable to the tooth root, which facilitates placement.
During manufacture, potentially antigenic portions of the collagen molecule are removed, resulting in a product that is highly biocompatible and well-tolerated by the tissue. The lack of immune response was verified during clinical investigation through over 350 dermal patch tests and blood serum analysis 1. In addition, each manufacturing lot of BioMend membranes is certified nonpyrogenic.
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The BioMend membrane serves as more than an inert barrier. By creating an environment where the wound can heal, the collagen membrane helps stabilize and maintain the blood clot in the defect site. The BioMend membrane absorbs completely into surrounding gingival connective tissue through enzyme (collagenase) degradation.
Made of Type 1 collagen, a predominant component of periodontal connective tissues, the membrane serves as a scaffold to augment flap thickness, and enhances primary wound coverage by attracting fibroblasts.* Its cross-linked structure provides easy handling characteristics and slows the degradation rate to allow more time for selective cells to repopulate the wound areas.*
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The BioMend membrane’s bioabsorbable nature which eliminates the need for a second surgical procedure for membrane removal. Because the absorption rate is controlled by the degree of cross-linking, BioMend membrane is designed to predictably remain intact for at least four weeks, functioning as a barrier during the critical period of wound healing. The membrane has an average retention of six to seven weeks. It is then fully absorbed by host enzymes into the surrounding tissue within eight weeks.
For easy handling and reduced inventory, the BioMend membrane is supplied in sheet form in three different sizes: 15mm x 20mm, 20mm x 30mm, and 30mm x 40mm. In sheet form, the material offers the clinician the flexibility of customization for specific defects. The product is non-friable and will not fray or fragment during modification.
The 15mm x 20mm membrane is large enough for the majority of defects, while the 20mm x 30mm size may be appropriate for large interproximal defects or distal defects. Both the 20mm x 30mm and 30mm x 40mm sizes may be selected to treat more than one defect on a particular patient by fashioning multiple membranes. However, unused material cannot be resterilized and must be discarded. Each size of the membrane is packaged as a single unit.
Each membrane is packaged within a sterile template envelope, which may be dropped directly onto a sterile field.
A sterile template made from medical-grade, high density polyethylene is included with each BioMend membrane to assist the clinician in shaping the membrane. Three popular pre-formed patterns are provided as a guide and may be conveniently punched out of the template, or the open area on the template may be used to trim a custom shape if desired.
*Bunyaratavej P, Wang H-L. Collagen membranes: A review. J Periodontol 2001;72:215-229.